My upgrade to the next generation of operating system for Macs has been uneventful, which is what you want to hear for major software upgrades. All of my major photo and general software is working without a hitch: Lightroom 4, Photoshop CS6, Office 2011, Twitter clients, Filemaker, and Moneydance. The only exception is Hotspot Shield, a VPN service for when I’m on the road and need to use hotspots. Not sure if the kernel panics are related to HS or something else, but for now, it’s removed.